Medicine information
Uses & overview
VILDIABATE M 500 by Steris Healthcare brings together two complementary blood sugar-lowering agents: Vildagliptin (50 mg) and Metformin Hydrochloride (500 mg). By combining a potent DPP-4 inhibitor with a biguanide, this dual-action formulation targets type 2 diabetes through two distinct, synergistic pathways—enhancing glucose-dependent insulin secretion and overcoming peripheral insulin resistance. Key Uses & Clinical Benefits: Synergistic Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients achieve and sustain target HbA1c goals. Incretin Enhancement: Vildagliptin (a DPP-4 inhibitor) prevents the rapid breakdown of incretin hormones (GLP-1 and GIP), boosting natural mealtime insulin release while suppressing excessive glucagon secretion. Reduces Hepatic Glucose Output: Metformin decreases glucose synthesis in the liver, reduces intestinal glucose absorption, and improves peripheral tissue sensitivity to circulating insulin. Low Risk of Hypoglycemia: Works primarily through glucose-dependent mechanisms, resulting in a low risk of low blood sugar spikes when used as directed. Weight-Neutral & Metabolic Support: Delivers comprehensive blood sugar management without causing body weight gain, supporting long-term metabolic health. How VILDIABATE M 500 Works: Vildagliptin (50 mg): Selectively inhibits the DPP-4 enzyme, raising active incretin hormone levels to stimulate pancreatic insulin output and inhibit inappropriate glucagon secretion in response to meals. Metformin Hydrochloride (500 mg): Activates AMP-activated protein kinase (AMPK) in liver tissue to suppress gluconeogenesis and enhance cellular glucose uptake in muscle cells.
How to use
Take 1 tablet of VILDIABATE M 500 twice daily with meals (preferably with breakfast and dinner) or strictly as prescribed by your physician. Taking the medication with food helps minimize potential gastrointestinal discomfort associated with Metformin. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
Storage
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
