Medicine information
Uses & overview
ATOVASTRIN EZ 80/10 by Steris Healthcare delivers an advanced fixed-dose combination of two complementary lipid-lowering agents: maximum-dose Atorvastatin (80 mg) and Ezetimibe (10 mg). Designed for patients requiring intense cholesterol reduction who fail to achieve target LDL goals on statin monotherapy alone, this dual formulation targets cholesterol through two distinct pathways—inhibiting both hepatic synthesis and intestinal absorption. Key Ingredients & Clinical Benefits: Atorvastatin (80 mg): A high-potency HMG-CoA reductase inhibitor (statin) that blocks the rate-limiting enzyme in hepatic cholesterol production. It dramatically lowers Low-Density Lipoprotein (LDL "bad" cholesterol), total cholesterol, and triglycerides while stabilizing vascular arterial plaques. Ezetimibe (10 mg): A selective cholesterol absorption inhibitor that targets the Niemann-Pick C1-Like 1 (NPC1L1) transporter in the small intestine. It blocks the absorption of biliary and dietary cholesterol, further lowering the cholesterol load delivered to the liver. Key Uses & Clinical Benefits: Maximal LDL-Cholesterol Reduction: Delivers synergistic cholesterol lowering beyond maximum-dose statin monotherapy, helping high-risk coronary patients achieve strict target lipid levels. Dual-Action Lipid Control: Targets cholesterol at both major sources—inhibiting internal liver synthesis and blocking external dietary/biliary intestinal absorption. Comprehensive Atherosclerosis Prevention: Inhibits fatty plaque accumulation within coronary and carotid arteries, keeping blood vessels flexible and reducing occlusion risks. Cardiovascular Event Reduction: Significantly lowers the incidence of major adverse cardiovascular events, including heart attack (myocardial infarction), stroke, and revascularization procedures. Single-Tablet Convenience: Combines maximum-strength dual lipid therapy into one convenient daily tablet, improving patient adherence to complex cardiovascular regimens.
How to use
Take 1 tablet of ATOVASTRIN EZ 80/10 once daily, with or without food (preferably in the evening or at bedtime), or strictly as prescribed by your cardiologist or physician. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. Maintain a healthy, low-fat diet and exercise routine throughout treatment for optimal lipid control.
Storage
Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
